abstract：:This study evaluated the roles of zeatin (2 mg/L) on direct organogenesis, phytochemical compounds, antioxidant activity, and cytotoxic activity in regenerated shoots of red cabbage. The results revealed that the extract of explant treated by 2 mg/L zeatin gives the highest content of total phenolics (5.18 mg gallic a...

journal_title：Natural product research

authors： Ravanfar SA,Karimi E,Mehrabanjoubani P,Ebrahimi M

更新日期：2020-03-01 00:00:00

abstract：:Morus nigra, popularly known as mulberry, has been traditionally used as anti-diabetic herbal medication. This study focused on hexane fraction from Brazilian M. nigra leaves (Hex-Mn) effects on digestion and absorption of carbohydrate in diabetic mice. The high-performance liquid chromatography (HPLC) analysis was pe...

journal_title：Natural product research

authors： Silva DHAD,Barbosa HM,Beltrão RLA,Silva CFO,Moura CA,Castro RN,Almeida JRGDS,Gomes DA,Lira EC

更新日期：2020-02-24 00:00:00

abstract：:Phytochemical investigation of the methanolic extract of Vangueria agrestis aerial parts led to the isolation and characterization of four monoterpene rhamnosides, two ursane saponins, and six flavonoid glycosides. Of these constituents, are three undescribed monoterpene glycosides, vangagrestosides A-C. The reported ...

journal_title：Natural product research

authors： Osman AG,Fantoukh O,Ali Z,Raman V,Ibrahim MA,Khan IA

更新日期：2020-02-24 00:00:00

abstract：:32 medicinal plants that are unique to the Russian Pharmacopeia have 693 isolated natural products associated with them (an average of 21.66 compounds per plant). This is in contrast to the US Pharmacopeia plants that have delivered 2366 known natural products (an average of 42.25 compounds per plant). ...

journal_title：Natural product research

authors： Chupakhin E,Babich O,Prosekov A,Asyakina L,Gureev M,Krasavin M

更新日期：2020-02-21 00:00:00

abstract：:The aim of this work was to provide information about kinetin effects on chemical volatile profile of Curcuma zedoaria (Christm.) Roscoe after several days of plant dormancy release. Rhizomes of C. zedoaria were immersed in four kinetin concentrations (0, 50, 100, 150 mg ml-1, n = 12 by each concentration) for 30 min....

journal_title：Natural product research

authors： Portella RO,Marques MOM,Ono EO,Silva PSSD,Fernandes AM,de Almeida LFR

更新日期：2020-02-21 00:00:00

abstract：:(+)-7-O-Methylisomiroestrol (MeI), a novel chromene, was discovered as a phytoestrogen in the Pueraria candollei var. mirifica (Airy Shaw & Suvat.) Niyomdham (PM) root having been used as an active agent against oestrogen depletion disorders. The identification of PM phytochemicals is crucial for the development of st...

journal_title：Natural product research

authors： Yusakul G,Juengsanguanpornsuk W,Sritularak B,Phaisan S,Juengwatanatrakul T,Putalun W

更新日期：2020-02-20 00:00:00

abstract：:Alzheimer's disease (AD) is a multifactorial health problem widespread over the world. Regarding the historical importance of the alkaloids in the central nervous system pharmacology they remain as promising drug candidates against AD. Seven alkaloids from Amaryllidaceae and Fabaceae were evaluated in vivo, in vitro a...

journal_title：Natural product research

authors： de Almeida WAM,de Andrade JP,Chacon DS,Lucas CR,Mariana E,de Santis Ferreira L,Guaratini T,Barbosa EG,Zuanazzi JA,Hallwass F,de Souza Borges W,de Paula Oliveira R,Giordani RB

更新日期：2020-02-18 00:00:00

abstract：:Two new oleanane triterpenoid saponins, bodiniosides Q (1) and R (2), along with five known saponins, niga-ichigoside F1 (3), 3-O-[β-D-glucopyranosyl]-28-O-[α-L-rhamnopyranosyl -(1→2)-β-D-glucopyranosyl] arjunolic acid (4), asiaticoside E (5), sericoside (6), and bodinioside E (7), were isolated from the aerial parts ...

journal_title：Natural product research

authors： Yang L,Zhang L,Du J,Shao L,Yu F,Li R,Zhong J

更新日期：2020-02-06 00:00:00

abstract：:Chemical investigation of Dendrobium plicatile Lindl resulted in the isolation and identification of one new bibenzyl, 2-chloro-3, 4'-dihydroxy-3',5-dimethoxybibenzyl (1), as well as 15 known stilbenoids. The structures of this new compound was elucidated by extensive spectroscopic analysis, including HRESIMS, 1H and ...

journal_title：Natural product research

authors： Chen DN,Wang YY,Liu WJ,Chen YJ,Wu YP,Wang JX,He F,Jiang L

更新日期：2020-02-01 00:00:00

abstract：:The whole plant, Tricholepis chaetolepis, powder was investigated using proximate and fluorescence analysis along with determining the extractive values. Total phenolics, flavonoids and total protein contents of n-hexane, chloroform and methanolic extracts of the whole plant were also determined. The anti-diabetic act...

journal_title：Natural product research

authors： Abbas A,Hassan SS,Sharif A,Ahmed S

更新日期：2020-02-01 00:00:00

abstract：:Alternanthera brasiliana is popularly known as 'penicillin' and used as an anti-inflammatory and for wound healing. The objective of this work was the phytochemical study of the species by analytical techniques such as LC-MS/MS and GC-MS. Twenty-seven compounds were identified, five by LC-MS and 22 by GC-MS analysis. ...

journal_title：Natural product research

authors： Alencar Filho JMT,Teixeira HAP,Sampaio PA,Pereira ECV,Amariz IAE,Rolim Neto PJ,Rolim LA,Araújo ECDC

更新日期：2020-02-01 00:00:00

abstract：:A new prenylated indole alkaloid, named paraherquamide J (1), together with four known compounds (2-5), were isolated from the mangrove rhizosphere soil-derived fungus Penicillium janthinellum HK1-6. The planar structure and relative configuration of 1 were determined by detailed analysis of the spectroscopic data esp...

journal_title：Natural product research

authors： Zheng YY,Shen NX,Liang ZY,Shen L,Chen M,Wang CY

更新日期：2020-02-01 00:00:00

abstract：:Two new compounds including a new 3-arylcoumarin liquiritcoumarin (1), and a new flavonoid glycoside crotoliquiritin (2), together with twelve known compounds (3-14) were isolated from the radix and rhizome of Glycyrrhiza uralensis. Their structures were elucidated on the basis of extensive spectroscopic data analyses...

journal_title：Natural product research

authors： Wang M,Yang W,Liu X,Liu Q,Zheng H,Wang X,Shen T,Wang S,Ren D

更新日期：2020-01-30 00:00:00

abstract：:Chemical investigation of the lichen Parmotrema dilatatum led to the isolation of a new chlorinated compound, named dilatatone (1), along with a known compound, sernanderin (2). Their chemical structures were determined by analysis of their 1 D and 2 D NMR spectra, HRESIMS, and ECD data. Both compounds showed weak α-g...

journal_title：Natural product research

authors： Phan HV,Devi AP,Le HD,Nguyen TT,Nguyen HH,Le TT,Nguyen TH,Sichaem J,Duong TH

更新日期：2020-01-27 00:00:00

abstract：:The search for bioactive compounds against diseases is imperative and the richness of the Amazon provides a large source to be explored. Current therapies for the treatment of parasitic infections have severe side effects and low efficacy, which makes the development of an effective chemotherapy extremely important. I...

journal_title：Natural product research

authors： Fernandes NS,Desoti VC,Dias A,da Silva YC,de Azevedo Dos Santos AP,Passarini GM,Nakamura CV,da Veiga Junior VF

更新日期：2020-01-25 00:00:00

abstract：:As part of our search for compounds with cytotoxicity from endophytes of traditional Chinese medicines, two novel nor-sesquiterpenoids (1-2) with a new skeleton containing a tetrahydrofuran moiety were isolated form a rice medium of Fusarium tricinctum, an endophytic fungus isolated from the root of Ligusticum chuanxi...

journal_title：Natural product research

authors： Cao YM,Guo DL,Jin MY,Tan L,Yang TL,Deng F,Gu YC,Li XH,Cao ZX,Deng Y

更新日期：2020-01-24 00:00:00

abstract：:The current study focuses on the chemical composition, and evaluation of antioxidant and antibacterial activity of the aerial parts of Centaurea resupinata subsp. dufourii. Using different chromatographic methods nine compounds 1-9 were isolated. The structural identification of isolated compounds was achieved using s...

journal_title：Natural product research

authors： Bouzghaia B,Moussa MTB,Goudjil R,Harkat H,Pale P

更新日期：2020-01-23 00:00:00

abstract：:A new alkynol, platycodynol (1), identified as 2, 3, 9, 13, 14-pentahydroxy-4, 6-tetradecadiyne, along with six known compounds (2-7) were obtained from Platycodins folium for the first time. Their structures were elucidated with infrared (IR), ultraviolet (UV), 1D and 2D nuclear magnetic resonance (NMR) spectroscopic...

journal_title：Natural product research

authors： Wang C,Dong Q,Wu F,Li Z,Li P,Liu J,Wang F

更新日期：2020-01-17 00:00:00

abstract：:Two new ditetrahydrofuran lignans, named sieverlignans A and B (1 and 2), together with six known ones (3-8), were isolated from the aerial parts of Artemisia sieversiana. Their structures were established on the basis of spectroscopic analysis including HRMS, NMR spectra and circular dichroism experiments. All the co...

journal_title：Natural product research

authors： Zhou XD,Xu XW,Shi LY,Chen SH,Zeng KW,Tu PF

更新日期：2020-01-13 00:00:00

abstract：:Okra, Abelmoschus esculentus L. (Moench), also known as Lady's Fingers, gombo, or bamje, is an annual plant belonging to the Malvaceae family. Traditional olistic medicine since centuries directly associates this plant and its parts to a beneficial health hypoglycemic effect. Since the abscisic acid (ABA) has been ass...

journal_title：Natural product research

authors： Daliu P,Annunziata G,Tenore GC,Santini A

更新日期：2020-01-01 00:00:00

abstract：:Physalins are seco-steroids with a variety of pharmacological activities already described. In this study the pharmacological properties of a standardized concentrated ethanolic extract from Physalis angulata (CEEPA), rich in physalins B, D, F and G, were studied in models of pain and inflammation in mice. Inflammator...

journal_title：Natural product research

authors： do Espírito Santo RF,Lima MDS,Juiz PJL,Opretzka LCF,Nogueira RC,Ribeiro IM,Tomassini TCB,Soares MBP,Villarreal CF

更新日期：2019-12-24 00:00:00

abstract：:A new cycloartane triterpene bisdesmoside, soulieoside T (1), and one known compound, oleanolic acid (2), were isolated from the ethanolic extract of the rhizomes of Actaea vaginata. Their structures were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compound 1 was evaluat...

journal_title：Natural product research

authors： Zhang M,Yang Q,Zhang X,Wu H

更新日期：2019-12-10 00:00:00

abstract：:Sanguisorba officinalis L. is a traditional herbal plant that belongs to the genus Sanguisorba and the family Rosaceae. A new ursane-type triterpenoid, 3-oxo-urs-11, 13(18)-dien-19, 28-olide (1), two known ursane-type triterpenoids (3 - 4) and three known oleanane-type triterpenoids (2, 5 - 6) were isolated from the r...

journal_title：Natural product research

authors： Wang R,Sun J,Jin M,Jin L,Qi Y,Cao L,Zhou W,Li G

更新日期：2019-12-04 00:00:00

abstract：:The chemical investigation of the leaves and stem bark of Acacia polyacantha (Fabaceae) led to the isolation of a new oleanane-type triterpenoid saponin named polyacanthoside A 1 together with fifteen known compounds. Their structures were established from spectral , mainly HRESIMS, 1D NMR and 2D NMR and by comparison...

journal_title：Natural product research

authors： Fotso W G,Na-Iya J,Mbaveng T A,Ango Yves P,Demirtas I,Kuete V,Samuel Y,Ngameni B,Efferth T,Ngadjui T B

更新日期：2019-12-01 00:00:00

abstract：:A continuous phytochemical study on the seeds of Senna obtusifolia (Syn.: Cassia obtusifolia) led to the isolation of a new anthraquinone analogue, obtusifolin-2-O-β-D-(6'-O-α,β-unsaturated butyryl)-glucopyranoside (1) and a new eurotinone analogue, epi-9-dehydroxyeurotinone-β-D-glucopyranoside (2). Their structures w...

journal_title：Natural product research

authors： Pang X,Wang LM,Zhang YC,Kang LP,Yu HS,Fan GW,Han LF

更新日期：2019-12-01 00:00:00

abstract：:In the present study, profiles of fatty acid, sn-2 fatty acid, triglyceride, phytochemical (including tocopherol/tocotrienol, phytosterol, flavonoid, carotenoid and polyphenol) and antioxidant capacity of extracts from the whole berry, pulp and seed of Hippophae¨ rhamnoides ssp. yunnanensis were investigated and compa...

journal_title：Natural product research

authors： Shi L,Zheng L,Zhao C,Jin Q,Wang X

更新日期：2019-12-01 00:00:00

abstract：:Two new monoterpene glucosides: xanmonoter A (1) and xanmonoter B (2) were isolated from Xanthium strumarium. Their structures were elucidated on the basis of 1D and 2D NMR, MS and CD analysis. Compounds 1 and 2 were tested for their anti-inflammatory activity with IC50 values of 17.4, 22.1 μM, respectively. ...

journal_title：Natural product research

authors： Jiang H,Xing X,Yan M,Guo X,Yang L,Yang L

更新日期：2019-12-01 00:00:00

abstract：:One known bis-indole alkaloid-voacamine was isolated from Voacanga africana Stapf and Surface Plasmon Resonance imaging (SPRi) exprement showed that this alkaloid could be combine with Protein Tyrosine Phosphatase1B (PTP1B). Then the PTP1B activity inhibition experiment display that the compound showed an outstanding ...

journal_title：Natural product research

authors： Wang YQ,Li HX,Liu XC,Zhao JS,Liu RQ,Huai WY,Ding WJ,Zhang TE,Deng Y

更新日期：2019-12-01 00:00:00

abstract：:Four C-13, C-14 side chain modified 9(R)-hydroxy-1-deoxy-taxane analogues 15, 16, 19 and 22 were semi-synthesized from 1-deoxybaccatin VI. The in vitro antitumor activity of these compounds was evaluated against A549 and A2780 cell lines. The preliminary SAR analysis showed that introduction of oxygen-containing group...

journal_title：Natural product research

authors： Tang P,Lin HX,Yuan TH,Cui YM

更新日期：2019-12-01 00:00:00

abstract：:This study is part of a wider investigation aimed to sustain the economical value of the by-products generated by the Citrus industry. In particular, the protected geographic indication (PGI) red orange of sicily (known as blood orange) has been analysed by HPLC and by the enzymatic AOAC method. All the by-products co...

journal_title：Natural product research

authors： Russo M,Bonaccorsi IL,Arigò A,Cacciola F,De Gara L,Dugo P,Mondello L

更新日期：2019-11-29 00:00:00

abstract：:The hexane and ethanol extracts from Himatanthus bracteatus (Apocynaceae) stems were evaluated for antiviral activity against Zika virus, yellow fever virus and dengue virus 2 and for cytotoxicity in Vero cells by MTT assay. The ethanol extract showed good antiviral activity against the three viruses with selective in...

journal_title：Natural product research

authors： da Silva ML,Stehmann JR,Serafim MSM,Vale VV,Gontijo DC,Brandão GC,Kroon EG,de Oliveira AB

更新日期：2019-11-20 00:00:00

abstract：:The actinomycete strain FIM06-0036 was isolated from marine sponge sample collected from the East China Sea and identified as Verrucosispora sp. based upon the results of 16S rRNA sequence analysis. One new alkaloid, 2-ethylhexyl 1H-imidazole-4-carboxylate (1), together with a known alkaloid butyl 1H-imidazole-4-carbo...

journal_title：Natural product research

authors： Chen MH,Lian YY,Fang DS,Chen L,Jia J,Zhang WL,Lin R,Xie Y,Bi HK,Jiang H

更新日期：2019-11-15 00:00:00

abstract：:A new butenolide derivative (1) featuring octyl substitution at γ-position, together with four known analogues (2-5) were isolated from marine-derived Streptomyces koyangensis SCSIO 5802. The structure of 1 was elucidated by HR-MS and NMR spectroscopic data analyses. The absolute configuration of the stereo centre in ...

journal_title：Natural product research

authors： Huang H,Song Y,Zang R,Wang X,Ju J

更新日期：2019-11-06 00:00:00

abstract：:New ent-trachylobane-3β-hydroperoxide (5) together with four known compounds, ricinine (1), trimethoxy ellagic acid (2), dimethoxy ellagic acid (3) and aleurotolic acid (4) were isolated from the methylene chloride fraction of the root bark of Chrozophora oblongifolia. The structures of these secondary metabolites wer...

journal_title：Natural product research

authors： Kamel MR,Nafady AM,Hassanein AMM,Hassan AR,Shimizu K,Ibrahim RR,Haggag EG

更新日期：2019-11-06 00:00:00

abstract：:Alkylglycerols (AKGs) are bioactive natural compounds that vary by alkyl chain length and degree of unsaturation, and their absolute configuration is 2S. Three AKGs (5l-5n) were synthesised in enantiomerically pure form, and were characterised for the first time together with 12 other known and naturally occurring AKG...

journal_title：Natural product research

authors： Fernández Montoya DJ,Contreras Jordan LA,Moreno-Murillo B,Silva-Gómez E,Mayorga-Wandurraga H

更新日期：2019-11-04 00:00:00

abstract：:Five phenanthrene and two dihydrophenanthrene derivatives were isolated from the diethyl ether extract of fresh rhizomes of Dioscorea communis (L.), among them a phenanthrentriol 1 reported for the first time from Dioscoreaceae family and two dihydrophenanthrene derivatives 6 and 7 reported also for the first time fro...

journal_title：Natural product research

authors： Boudjada A,Touil A,Bensouici C,Bendif H,Rhouati S

更新日期：2019-11-01 00:00:00

abstract：:A novel monoterpenoid indole alkaloid, melognine (1) possessing an unprecedented skeleton with a 6/6/5/5/6/6 hexatomic rearranged ring system was isolated from the stems of Melodinus fusiformis. The structure with absolute configuration of 1 was established by extensive spectroscopic analyses and quantum ECD calculati...

journal_title：Natural product research

authors： Zhou J,Du SY,Fang ZY,Feng JH

更新日期：2019-11-01 00:00:00

abstract：:In this study the crude ethyl acetate extracts and fractions from red algae Gracilaria edulis were studied against fish pathogens. G. edulis was extracted with ethyl acetate, fractionated in silica gel coloum chromatography and gradient hexane-ethyl acetate. The extract and fractions were subjected for bioassay guided...

journal_title：Natural product research

authors： Kasanah N,Amelia W,Mukminin A,Triyanto,Isnansetyo A

更新日期：2019-11-01 00:00:00

abstract：:A new protostane-type triterpenoid bearing an oxetane ring in the side-chain, named alisol W (1), has been obtained from the dried rhizome of Alisma plantago-aquatica subsp. orientale. The structure and absolute configuration of compound 1 was determined from extensive spectroscopic analysis. In addition, the vasorela...

journal_title：Natural product research

authors： Li HM,Liu D,Dai WF,Chen XQ,Li RT

更新日期：2019-11-01 00:00:00

abstract：:The aerial parts of Allium eriophyllum Var. eriophyllum (Syn. A. longisepalum Bertol.) were collected at full flowering stage.The essential oil was isolated by hydro distillation and analyzed by a combination of capillary GC and GC-MS. The main components were carvacrol (71.54%), Methyl (methylthio) methyl disulfide (...

journal_title：Natural product research

authors： Mosavi H,Alizadeh A

更新日期：2019-11-01 00:00:00